How Do I Know If I’ve Got It? Depression is more than just a period of feeling down – it is something that can dominate the mind, body and soul, changing the way you think and behave. It can impact on every part of your life. Often people who are depressed don’t enjoy things they used to, lose their libido, have little energy, can’t sleep or eat, feel anxious, feel worthless, gain weight and more. Most people simply get used to living this way and accept it. But if you feel you do suffer as a result, there is help.